The METHYL SULFONYL METHANE is a natural form of organic sulfur, the chemical formula of which is CH 3 SO₂CH₃. This is the form in which sulfur is present in nature within all living organisms, where it acts as a biologically active substance. Methyl Sulfonyl Methane is an odorless, white, crystalline powder that is highly soluble in hot water and a wide variety of organic solvents. Organic sulfur, biologically active, possesses incredible therapeutic and preventive properties. It has medicinal properties so complete, and based on such obvious principles, that its discovery is normally counted among the most important advances that have been made in orthomolecular medicine in the second half of the twentieth century. To find out more, see the booklet “The Methyl Sulfonyl Methane miracle“. The leaves of HOREHOUND (Marrubium vulgare) contain diterpene lactones (marrubin, 0.3-1%),  mucilage, pectins, flavonoids, alkaloids, betonicin,  mineral salts and essential oil. Horehound was already used in ancient times against respiratory diseases. The Greek physician Dioscorides  (40-90 BC) already recommended it to relieve tuberculosis, asthma and coughs. In 1597 the English herbalist Jhon Gerard praised this plant as “a remedy of the most remarkable against coughs and breathing difficulties“. Marrubina  is a powerful expectorant and bitter. Horehound is used in the treatment of breathing difficulties, bronchitis, pathological dilatation of the bronchi (bronchiectasis), asmiform bronchitis, dry coughs and whooping cough. The BLACKCURRANT (Ribes nigrum) it is the remedy for acute allergy, chronic gouty states and minor azotemic renal insufficiency. The gems contain large quantities of the active ingredients, probably of a steroid nature, which they have a cortisone-like action. Every acute adynamic syndrome finds Ribes nigrum its indispensable remedy to raise the corticosteroid rate. Its action is exercised at the level of the adrenal cortex, of which it seems to stimulate the secretion of anti-inflammatory hormones. It has a clear anti-allergic action, it is indicated in all inflammatory states where the speed of sedimentation is very accelerated and in allergic cases whatever their clinical appearance:  rhinitis, bronchitis, asthma, gastritis, migraines, urticaria, Quincke’s edema, allergic rheumatism. The LACTOBACILLUS ACIDOPHYLUS It safeguards and regenerates the intestinal bacterial flora, from where, according to some authors, the infectious process starts and does so by maintaining the intestinal pH around 4-5,  thus not giving the possibility of growth to those “not good” bacteria that would grow on a soil with an acid or basic pH. The MANGANESE gluconate is the trace element of the first diathesis (allergic or arthritic) and it is the diathesis where symptoms such as allergic disorders of various kinds are found. In this miscellaneous it was considered important to use gluconate as organic salts offer various advantages, they have a mixed water/fat solubility therefore a guarantee of good absorption, easy ionizability given that the acid has a higher dissolution coefficient. Gluconic acid is used to manufacture almost all trace elements, it is the first derivative of the oxidation of glucose, and it is the physiological monosaccharide par excellence. The more thorough oxidation of gluconic acid (in our body) leads to glucuronic acid which is the internal cleansing agent in charge of eliminating agents toxic, in fact, glucuroconjugation represents one of the main detoxification pathways. Gluconates are easily split, releasing metal catalysts and providing the body, through the transformation of gluconic acid, with a tool to improve its detoxification.